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Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again

Ras is the most frequently mutated oncogene and recent drug development efforts have spurred significant new research interest. Here we review progress toward understanding how Ras functions in nanoscale, proteo-lipid signaling complexes on the plasma membrane, called nanoclusters. We discuss how G-...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Abankwa, Daniel, Gorfe, Alemayehu A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694788/
https://ncbi.nlm.nih.gov/pubmed/33172116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111522
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