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ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold
Ras-induced senescence mediated through ASPP2 represents a barrier to tumour formation. It is initiated by ASPP2’s interaction with Ras at the plasma membrane, which stimulates the Raf/MEK/ERK signaling cascade. Ras to Raf signalling requires Ras to be organized in nanoscale signalling complexes, ca...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4954646/ https://ncbi.nlm.nih.gov/pubmed/27437940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159677 |
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