Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A

The kinesin-8 motor, KIF19A, accumulates at cilia tips and controls cilium length. Defective KIF19A leads to hydrocephalus and female infertility because of abnormally elongated cilia. Uniquely among kinesins, KIF19A possesses the dual functions of motility along ciliary microtubules and depolymeriz...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Wang, Doudou, Nitta, Ryo, Morikawa, Manatsu, Yajima, Hiroaki, Inoue, Shigeyuki, Shigematsu, Hideki, Kikkawa, Masahide, Hirokawa, Nobutaka
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2016
Sujets:
Biophysics and Structural Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045296/
https://ncbi.nlm.nih.gov/pubmed/27690357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18101
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