X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding

The molecular motor kinesin moves along microtubules using energy from ATP hydrolysis in an initial step coupled with ADP release. In neurons, kinesin-1/KIF5C preferentially binds to the GTP-state microtubules over GDP-state microtubules to selectively enter an axon among many processes; however, be...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO J
Päätekijät: Morikawa, Manatsu, Yajima, Hiroaki, Nitta, Ryo, Inoue, Shigeyuki, Ogura, Toshihiko, Sato, Chikara, Hirokawa, Nobutaka
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2015
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426485/
https://ncbi.nlm.nih.gov/pubmed/25777528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201490588
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