Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only a subset of microtubules for transport in living cells. This biased use of microtubules is proposed as the guidance cue for polarized transport in neurons, but the underlying mechanisms are still poorly under...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Shima, Tomohiro, Morikawa, Manatsu, Kaneshiro, Junichi, Kambara, Taketoshi, Kamimura, Shinji, Yagi, Toshiki, Iwamoto, Hiroyuki, Uemura, Sotaro, Shigematsu, Hideki, Shirouzu, Mikako, Ichimura, Taro, Watanabe, Tomonobu M., Nitta, Ryo, Okada, Yasushi, Hirokawa, Nobutaka
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279379/
https://ncbi.nlm.nih.gov/pubmed/30297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711178
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