Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only a subset of microtubules for transport in living cells. This biased use of microtubules is proposed as the guidance cue for polarized transport in neurons, but the underlying mechanisms are still poorly under...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Shima, Tomohiro, Morikawa, Manatsu, Kaneshiro, Junichi, Kambara, Taketoshi, Kamimura, Shinji, Yagi, Toshiki, Iwamoto, Hiroyuki, Uemura, Sotaro, Shigematsu, Hideki, Shirouzu, Mikako, Ichimura, Taro, Watanabe, Tomonobu M., Nitta, Ryo, Okada, Yasushi, Hirokawa, Nobutaka
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279379/
https://ncbi.nlm.nih.gov/pubmed/30297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711178
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