Kinesin-binding–triggered conformation switching of microtubules contributes to polarized transport

Kinesin-1, the founding member of the kinesin superfamily of proteins, is known to use only a subset of microtubules for transport in living cells. This biased use of microtubules is proposed as the guidance cue for polarized transport in neurons, but the underlying mechanisms are still poorly under...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Shima, Tomohiro, Morikawa, Manatsu, Kaneshiro, Junichi, Kambara, Taketoshi, Kamimura, Shinji, Yagi, Toshiki, Iwamoto, Hiroyuki, Uemura, Sotaro, Shigematsu, Hideki, Shirouzu, Mikako, Ichimura, Taro, Watanabe, Tomonobu M., Nitta, Ryo, Okada, Yasushi, Hirokawa, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279379/
https://ncbi.nlm.nih.gov/pubmed/30297389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201711178
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