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Autoinhibition of a neuronal kinesin UNC-104/KIF1A regulates the size and density of synapses

Kinesin motor proteins transport intracellular cargos throughout cells by hydrolyzing ATP and moving along microtubule tracks. Intramolecular autoinhibitory interactions have been shown for several kinesins in vitro, however, the physiological significance of autoinhibition remains poorly understood...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Niwa, Shinsuke, Lipton, David M., Morikawa, Manatsu, Zhao, Charles, Hirokawa, Nobutaka, Lu, Hang, Shen, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432123/
https://ncbi.nlm.nih.gov/pubmed/27524618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.043
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