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Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy
Microtubules are dynamic polymers that stochastically switch between growing and shrinking phases. Microtubule dynamics are regulated by guanosine triphosphate (GTP) hydrolysis by β-tubulin, but the mechanism of this regulation remains elusive because high-resolution microtubule structures have only...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413364/ https://ncbi.nlm.nih.gov/pubmed/22851320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201161 |
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