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Transformation of taxol-stabilized microtubules into inverted tubulin tubules triggered by a tubulin conformation switch
Bundles of taxol-stabilized microtubules (MTs) – hollow tubules comprised of assembled αβ-tubulin heterodimers – spontaneously assemble above a critical concentration of tetravalent spermine and are stable over long times at room temperature. Here we report that at concentrations of spermine several...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3946914/ https://ncbi.nlm.nih.gov/pubmed/24441880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3858 |
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