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Radial Compression of Microtubules and the Mechanism of Action of Taxol and Associated Proteins
Microtubules (MTs) are hollow cylindrical polymers composed of αβ-tubulin heterodimers that align head-to-tail in the MT wall, forming linear protofilaments that interact laterally. We introduce a probe of the interprotofilament interactions within MTs and show that this technique gives insight into...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Biophysical Society
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366837/ https://ncbi.nlm.nih.gov/pubmed/16100275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.057679 |
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