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Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor

The complement system plays a key role in innate immunity, inflammation, and coagulation. The system is delicately balanced by negative regulatory mechanisms that modulate the host response to pathogen invasion and injury. The serpin, C1-esterase inhibitor (C1-INH), is the only known plasma inhibito...

詳細記述

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書誌詳細
出版年:Blood
主要な著者: Wijeyewickrema, Lakshmi C., Lameignere, Emilie, Hor, Lilian, Duncan, Renee C., Shiba, Toshikazu, Travers, Richard J., Kapopara, Piyushkumar R., Lei, Victor, Smith, Stephanie A., Kim, Hugh, Morrissey, James H., Pike, Robert N., Conway, Edward M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5043130/
https://ncbi.nlm.nih.gov/pubmed/27338096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-699561
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