Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA

Anticoagulant therapy–associated bleeding and pathological thrombosis pose serious risks to hospitalized patients. Both complications could be mitigated by developing new therapeutics that safely neutralize anticoagulant activity and inhibit activators of the intrinsic blood clotting pathway, such a...

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Foilsithe in:Blood
Main Authors: Kalathottukaren, Manu Thomas, Abraham, Libin, Kapopara, Piyushkumar R., Lai, Benjamin F. L., Shenoi, Rajesh A., Rosell, Federico I., Conway, Edward M., Pryzdial, Edward L. G., Morrissey, James H., Haynes, Charles A., Kizhakkedathu, Jayachandran N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2017
Ábhair:
Thrombosis and Hemostasis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345737/
https://ncbi.nlm.nih.gov/pubmed/28034889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-747915
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