Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA

Anticoagulant therapy–associated bleeding and pathological thrombosis pose serious risks to hospitalized patients. Both complications could be mitigated by developing new therapeutics that safely neutralize anticoagulant activity and inhibit activators of the intrinsic blood clotting pathway, such a...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Kalathottukaren, Manu Thomas, Abraham, Libin, Kapopara, Piyushkumar R., Lai, Benjamin F. L., Shenoi, Rajesh A., Rosell, Federico I., Conway, Edward M., Pryzdial, Edward L. G., Morrissey, James H., Haynes, Charles A., Kizhakkedathu, Jayachandran N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345737/
https://ncbi.nlm.nih.gov/pubmed/28034889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-747915
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