Nontoxic polyphosphate inhibitors reduce thrombosis while sparing hemostasis

Polyphosphate (polyP) is secreted by activated platelets and has been shown to contribute to thrombosis, suggesting that it could be a novel antithrombotic target. Previously reported polyP inhibitors based on polycationic substances, such as polyethylenimine, polyamidoamine dendrimers, and polymyxi...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Travers, Richard J., Shenoi, Rajesh A., Kalathottukaren, Manu Thomas, Kizhakkedathu, Jayachandran N., Morrissey, James H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Plenary Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239329/
https://ncbi.nlm.nih.gov/pubmed/25202141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-577932
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