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Design of Polyphosphate Inhibitors: a Molecular Dynamics Investigation on Polyethylene glycol-linked Cationic Binding Groups
Inorganic polyphosphate (polyP) released by human platelets has recently been shown to activate blood clotting and identified as a potential target for the development of novel antithrombotics. Recent studies have shown that polymers with cationic binding groups (CBGs) inhibit polyP and attenuate th...
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| Udgivet i: | Biomacromolecules |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6384525/ https://ncbi.nlm.nih.gov/pubmed/29539260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.8b00327 |
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