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Inhibition of polyphosphate as a novel strategy for preventing thrombosis and inflammation

Inorganic polyphosphates are linear polymers of orthophosphate that modulate blood clotting and inflammation. Polyphosphate accumulates in infectious microorganisms and is secreted by activated platelets; long-chain polyphosphate in particular is an extremely potent initiator of the contact pathway,...

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Detalhes bibliográficos
Main Authors: Smith, Stephanie A., Choi, Sharon H., Collins, Julie N. R., Travers, Richard J., Cooley, Brian C., Morrissey, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537307/
https://ncbi.nlm.nih.gov/pubmed/22968458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-444935
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