Polyphosphate suppresses complement via the terminal pathway

Polyphosphate, synthesized by all cells, is a linear polymer of inorganic phosphate. When released into the circulation, it exerts prothrombotic and proinflammatory activities by modulating steps in the coagulation cascade. We examined the role of polyphosphate in regulating the evolutionarily relat...

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Bibliografiset tiedot
Päätekijät: Wat, Jovian M., Foley, Jonathan H., Krisinger, Michael J., Ocariza, Linnette Mae, Lei, Victor, Wasney, Gregory A., Lameignere, Emilie, Strynadka, Natalie C., Smith, Stephanie A., Morrissey, James H., Conway, Edward M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2014
Aiheet:
Thrombosis and Hemostasis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907762/
https://ncbi.nlm.nih.gov/pubmed/24335501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-515726
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