Polyphosphate suppresses complement via the terminal pathway

Polyphosphate, synthesized by all cells, is a linear polymer of inorganic phosphate. When released into the circulation, it exerts prothrombotic and proinflammatory activities by modulating steps in the coagulation cascade. We examined the role of polyphosphate in regulating the evolutionarily relat...

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Detalhes bibliográficos
Main Authors: Wat, Jovian M., Foley, Jonathan H., Krisinger, Michael J., Ocariza, Linnette Mae, Lei, Victor, Wasney, Gregory A., Lameignere, Emilie, Strynadka, Natalie C., Smith, Stephanie A., Morrissey, James H., Conway, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907762/
https://ncbi.nlm.nih.gov/pubmed/24335501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-515726
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