Polyphosphate suppresses complement via the terminal pathway

Polyphosphate, synthesized by all cells, is a linear polymer of inorganic phosphate. When released into the circulation, it exerts prothrombotic and proinflammatory activities by modulating steps in the coagulation cascade. We examined the role of polyphosphate in regulating the evolutionarily relat...

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Библиографические подробности
Главные авторы: Wat, Jovian M., Foley, Jonathan H., Krisinger, Michael J., Ocariza, Linnette Mae, Lei, Victor, Wasney, Gregory A., Lameignere, Emilie, Strynadka, Natalie C., Smith, Stephanie A., Morrissey, James H., Conway, Edward M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
Предметы:
Thrombosis and Hemostasis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907762/
https://ncbi.nlm.nih.gov/pubmed/24335501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-515726
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