Id3 Orchestrates Germinal Center B Cell Development

Previous studies have demonstrated that E proteins induce activation-induced deaminase (AID) expression in activated B cells. Here, we examined the role of Id3 in germinal center (GC) cells. We found that Id3 expression is high in follicular B lineage cells but declines in GC cells. Immunized mice w...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Chen, Shuwen, Miyazaki, Masaki, Chandra, Vivek, Fisch, Kathleen M., Chang, Aaron N., Murre, Cornelis
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038142/
https://ncbi.nlm.nih.gov/pubmed/27457619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00150-16
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