Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate

The genome is folded into domains located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with intra-domai...

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Detalhes bibliográficos
Main Authors: Lin, Yin C, Benner, Christopher, Mansson, Robert, Heinz, Sven, Miyazaki, Kazuko, Miyazaki, Masaki, Chandra, Vivek, Bossen, Claudia, Glass, Christopher K, Murre, Cornelis
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501570/
https://ncbi.nlm.nih.gov/pubmed/23064439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2432
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