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Global changes in nuclear positioning of genes and intra- and inter-domain genomic interactions that orchestrate B cell fate
The genome is folded into domains located in either transcriptionally inert or permissive compartments. Here we used genome-wide strategies to characterize domains during B cell development. Structured Interaction Matrix Analysis revealed that CTCF occupancy was primarily associated with intra-domai...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501570/ https://ncbi.nlm.nih.gov/pubmed/23064439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2432 |
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