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The Establishment of B versus T Cell Identity

In B cell progenitors, E-proteins E2A and HEB are critical to induce a B-lineage specific program of gene expression and orchestrate the assembly of the immunoglobulin loci. In the thymus E2A and HEB act differently, activating the expression of genes closely associated with the establishment of T c...

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Autores principales: Miyazaki, Kazuko, Miyazaki, Masaki, Murre, Cornelis
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030559/
https://ncbi.nlm.nih.gov/pubmed/24679436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.02.009
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