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Brg1 activates enhancer repertoires to establish B cell identity and modulate cell growth

Early B cell development is orchestrated by the combined activities of the transcriptional regulators E2A, EBF1, Foxo1 and Ikaros. However, how the genome-wide binding patterns of these regulators are modulated during B-lineage development remains to be determined. Here, we found that in lymphoid pr...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Bossen, Claudia, Murre, Caroline S, Chang, Aaron N, Mansson, Robert, Rodewald, Hans-Reimer, Murre, Cornelis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4474778/
https://ncbi.nlm.nih.gov/pubmed/25985234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3170
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