The E-Id Axis Instructs Adaptive Versus Innate Lineage Cell Fate Choice and Instructs Regulatory T Cell Differentiation

Immune responses are primarily mediated by adaptive and innate immune cells. Adaptive immune cells, such as T and B cells, evoke antigen-specific responses through the recognition of specific antigens. This antigen-specific recognition relies on the V(D)J recombination of immunoglobulin (Ig) and T c...

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Main Authors: Reiko Hidaka, Kazuko Miyazaki, Masaki Miyazaki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Immunology
Assuntos:
T cell versus ILCs
Rag gene expression
E-Id axis
T-lineage commitment
Treg differentiation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.890056/full
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