Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease

Regulatory T (T(reg)) cells suppress the development of inflammatory disease, but our knowledge of transcriptional regulators that control this function remains incomplete. Here we show that expression of Id2 and Id3 in T(reg) cells was required to suppress development of fatal inflammatory disease....

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Bibliographic Details
Published in:Nat Immunol
Main Authors: Miyazaki, Masaki, Miyazaki, Kazuko, Chen, Shuwen, Itoi, Manami, Miller, Marina, Lu, Li-Fan, Varki, Nissi, Chang, Aaron N, Broide, David H, Murre, Cornelis
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365819/
https://ncbi.nlm.nih.gov/pubmed/24973820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2928
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