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Id3 Orchestrates Germinal Center B Cell Development
Previous studies have demonstrated that E proteins induce activation-induced deaminase (AID) expression in activated B cells. Here, we examined the role of Id3 in germinal center (GC) cells. We found that Id3 expression is high in follicular B lineage cells but declines in GC cells. Immunized mice w...
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Publié dans: | Mol Cell Biol |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5038142/ https://ncbi.nlm.nih.gov/pubmed/27457619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00150-16 |
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