Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development

The generation of high-affinity antibodies requires germinal center (GC) development and differentiation of long-lived plasma cells in a multilayered process that is tightly controlled by the activity of multiple transcription factors. Here, we reveal a new layer of complexity by demonstrating that...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Gloury, Renee, Zotos, Dimitra, Zuidscherwoude, Malou, Masson, Frederick, Liao, Yang, Hasbold, Jhaguaral, Corcoran, Lynn M., Hodgkin, Phil D., Belz, Gabrielle T., Shi, Wei, Nutt, Stephen L., Tarlinton, David M., Kallies, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886367/
https://ncbi.nlm.nih.gov/pubmed/27217539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20152003
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