Id2-Mediated Inhibition of E2A Represses Memory CD8(+) T Cell Differentiation

The transcription factor inhibitor of DNA binding (Id)2 modulates T cell fate decisions, but the molecular mechanism underpinning this regulation is unclear. In this study we show that loss of Id2 cripples effector differentiation and instead programs CD8(+) T cells to adopt a memory fate with incre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Masson, Frederick, Minnich, Martina, Olshansky, Moshe, Bilic, Ivan, Mount, Adele M., Kallies, Axel, Speed, Terence P., Busslinger, Meinrad, Nutt, Stephen L., Belz, Gabrielle T.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Immune Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631715/
https://ncbi.nlm.nih.gov/pubmed/23536629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300099
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados