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Blimp-1 controls plasma cell function through regulation of immunoglobulin secretion and the unfolded protein response
Plasma cell differentiation requires silencing of B cell transcription, while establishing antibody-secretory function and long-term survival. The transcription factors Blimp-1 and IRF4 are essential for plasma cell generation, however their function in mature plasma cells has remained elusive. We h...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4757736/ https://ncbi.nlm.nih.gov/pubmed/26779600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3348 |
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