A carregar...

Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self‐reactive plasma cells

The transcription factor Blimp1 is not only an essential regulator of plasma cells, but also a risk factor for the development of autoimmune disease in humans. Here, we demonstrate in the mouse that the Prdm1 (Blimp1) gene was partially activated at the chromatin and transcription level in early B c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Bönelt, Peter, Wöhner, Miriam, Minnich, Martina, Tagoh, Hiromi, Fischer, Maria, Jaritz, Markus, Kavirayani, Anoop, Garimella, Manasa, Karlsson, Mikael CI, Busslinger, Meinrad
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331720/
https://ncbi.nlm.nih.gov/pubmed/30498131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!