Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells

B-cell lineage-specific activator protein (BSAP), encoded by the Pax-5 gene, is critical for B-cell lineage commitment and B-cell development but is not expressed in terminally differentiated B cells. We demonstrate a direct connection between BSAP and B-lymphocyte-induced maturation protein 1 (Blim...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Kuo-I, Angelin-Duclos, Cristina, Kuo, Tracy C., Calame, Kathryn
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133916/
https://ncbi.nlm.nih.gov/pubmed/12052884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4771-4780.2002
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