Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow

Long-lived plasma cells, residing primarily in the bone marrow, continuously secrete antibody and provide an important component of humoral memory. However, when such cells secrete autoantibodies or become transformed, they can be pathogenic. We have shown recently that the transcriptional repressor...

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Bibliographic Details
Main Authors: Shapiro-Shelef, Miriam, Lin, Kuo-I, Savitsky, David, Liao, Jerry, Calame, Kathryn
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213334/
https://ncbi.nlm.nih.gov/pubmed/16314438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051611
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