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Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow

Long-lived plasma cells, residing primarily in the bone marrow, continuously secrete antibody and provide an important component of humoral memory. However, when such cells secrete autoantibodies or become transformed, they can be pathogenic. We have shown recently that the transcriptional repressor...

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Hlavní autoři: Shapiro-Shelef, Miriam, Lin, Kuo-I, Savitsky, David, Liao, Jerry, Calame, Kathryn
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213334/
https://ncbi.nlm.nih.gov/pubmed/16314438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051611
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