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B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion

B-1 B cells produce circulating natural antibodies that provide “innate-like” protection against bacterial and viral pathogens. They also provide adaptive responses to blood and air-borne pathogens. B lymphocyte–induced maturation protein 1 (Blimp-1) is a transcriptional repressor that is required f...

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Bibliografiske detaljer
Main Authors: Savitsky, David, Calame, Kathryn
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118107/
https://ncbi.nlm.nih.gov/pubmed/16954370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060411
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