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Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene, NLRP12/Monarch-1
NLR (nucleotide-binding domain, leucine-rich repeat) proteins are intracellular regulators of host defense and immunity. One NLR gene, NLRP12/Monarch-1, has emerged as an important inhibitor of inflammatory gene expression in human myeloid cells. This is supported by genetic analysis linking the los...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701146/ https://ncbi.nlm.nih.gov/pubmed/19234190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801692 |
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