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Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene, NLRP12/Monarch-1

NLR (nucleotide-binding domain, leucine-rich repeat) proteins are intracellular regulators of host defense and immunity. One NLR gene, NLRP12/Monarch-1, has emerged as an important inhibitor of inflammatory gene expression in human myeloid cells. This is supported by genetic analysis linking the los...

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Detalhes bibliográficos
Main Authors: Lord, Christopher A., Savitsky, David, Sitcheran, Raquel, Calame, Kathryn, Wright, Jo Rae, Pan-Yun Ting, Jenny, Williams, Kristi L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701146/
https://ncbi.nlm.nih.gov/pubmed/19234190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801692
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