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Paneth cell defects in Crohn’s disease patients promote dysbiosis
BACKGROUND. Paneth cell dysfunction has been implicated in a subset of Crohn’s disease (CD) patients. We previously stratified clinical outcomes of CD patients by using Paneth cell phenotypes, which we defined by the intracellular distribution of antimicrobial proteins. Animal studies suggest that P...
में बचाया:
| में प्रकाशित: | JCI Insight |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2016
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033844/ https://ncbi.nlm.nih.gov/pubmed/27699268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86907 |
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