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Paneth cell defects in Crohn’s disease patients promote dysbiosis

BACKGROUND. Paneth cell dysfunction has been implicated in a subset of Crohn’s disease (CD) patients. We previously stratified clinical outcomes of CD patients by using Paneth cell phenotypes, which we defined by the intracellular distribution of antimicrobial proteins. Animal studies suggest that P...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Liu, Ta-Chiang, Gurram, Bhaskar, Baldridge, Megan T., Head, Richard, Lam, Vy, Luo, Chengwei, Cao, Yumei, Simpson, Pippa, Hayward, Michael, Holtz, Mary L., Bousounis, Pavlos, Noe, Joshua, Lerner, Diana, Cabrera, Jose, Biank, Vincent, Stephens, Michael, Huttenhower, Curtis, McGovern, Dermot P.B., Xavier, Ramnik J., Stappenbeck, Thaddeus S., Salzman, Nita H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033844/
https://ncbi.nlm.nih.gov/pubmed/27699268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.86907
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