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Paneth cell defensins and the regulation of the microbiome: Détente at mucosal surfaces
Recently, our laboratory demonstrated that Paneth cell defensins, innate antimicrobial peptides that contribute to mucosal host defense, are able to regulate the composition of the intestinal bacterial microbiome. Using complementary mouse models of defensin deficiency (MMP 7(−/−)) and surplus (HD 5...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2010
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3056107/ https://ncbi.nlm.nih.gov/pubmed/21468224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.1.6.14076 |
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