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Reduced Paneth cell α-defensins in ileal Crohn's disease

The pathogenesis of Crohn′s disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal bacteria that may initiate and perpetuate mucosal inflammation in genetically susceptible individuals. Paneth cells (PC) are the major source of antimicrobial peptides in the sma...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Wehkamp, Jan, Salzman, Nita H., Porter, Edith, Nuding, Sabine, Weichenthal, Michael, Petras, Robert E., Shen, Bo, Schaeffeler, Elke, Schwab, Matthias, Linzmeier, Rose, Feathers, Ryan W., Chu, Hiutung, Lima, Heriberto, Fellermann, Klaus, Ganz, Tomas, Stange, Eduard F., Bevins, Charles L.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1306791/
https://ncbi.nlm.nih.gov/pubmed/16330776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505256102
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