A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon

Defensins are endogenous antimicrobial peptides that protect the intestinal mucosa against bacterial invasion. It has been suggested that deficient defensin expression may underlie the chronic inflammation of Crohn disease (CD). The DNA copy number of the beta-defensin gene cluster on chromosome 8p2...

詳細記述

保存先:
書誌詳細
主要な著者: Fellermann, Klaus, Stange, Daniel E., Schaeffeler, Elke, Schmalzl, Hartmut, Wehkamp, Jan, Bevins, Charles L., Reinisch, Walter, Teml, Alexander, Schwab, Matthias, Lichter, Peter, Radlwimmer, Bernhard, Stange, Eduard F.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society of Human Genetics 2006
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1559531/
https://ncbi.nlm.nih.gov/pubmed/16909382
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料