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Reduced mucosal antimicrobial activity in Crohn's disease of the colon
OBJECTIVES: In order to maintain the mucosal barrier against luminal microorganisms the intestinal epithelial cells synthesise various broad‐spectrum antimicrobial peptides including defensins and cathelicidins. Recent studies indicate that both may be deficient in Crohn's disease. To elucidate...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMJ Group
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1954969/ https://ncbi.nlm.nih.gov/pubmed/17456510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.118646 |
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