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Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase

The prototypical second messenger cAMP regulates a wide variety of physiological processes. It can simultaneously mediate diverse functions by acting locally within independently-regulated microdomains. In mammalian cells, two types of adenylyl cyclase generate cAMP; G protein regulated transmembran...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem Biol
Asıl Yazarlar: Ramos-Espiritu, Lavoisier, Kleinboelting, Silke, Navarrete, Felipe A., Alvau, Antonio, Visconti, Pablo E., Valsecchi, Federica, Starkov, Anatoly, Manfredi, Giovanni, Buck, Hannes, Adura, Carolina, Zippin, Jonathan H., van den Heuvel, Joop, Glickman, J. Fraser, Steegborn, Clemens, Levin, Lonny R., Buck, Jochen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030147/
https://ncbi.nlm.nih.gov/pubmed/27547922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2151
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