טוען...
Application of physiologically based pharmacokinetic modeling in predicting drug–drug interactions for sarpogrelate hydrochloride in humans
BACKGROUND: Evaluating the potential risk of metabolic drug–drug interactions (DDIs) is clinically important. OBJECTIVE: To develop a physiologically based pharmacokinetic (PBPK) model for sarpogrelate hydrochloride and its active metabolite, (R,S)-1-{2-[2-(3-methoxyphenyl)ethyl]-phenoxy}-3-(dimethy...
שמור ב:
| הוצא לאור ב: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Dove Medical Press
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5028085/ https://ncbi.nlm.nih.gov/pubmed/27695293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S109141 |
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