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Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice

Pravastatin is a lipid-lowering agent that attenuates atherosclerosis. However, the multifactorial pathogenesis of atherosclerosis requires other drugs with different anti-atherogenic mechanisms. We chose sarpogrelate as an anti-platelet agent and a novel component of a complex drug with pravastatin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Park, Kyung-Yeon, Oh, Euichaul, Kwak, Mi-Kyoung, Jun, Hyun Sik, Heo, Tae-Hwe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780828/
https://ncbi.nlm.nih.gov/pubmed/26950217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150791
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