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Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice

Pravastatin is a lipid-lowering agent that attenuates atherosclerosis. However, the multifactorial pathogenesis of atherosclerosis requires other drugs with different anti-atherogenic mechanisms. We chose sarpogrelate as an anti-platelet agent and a novel component of a complex drug with pravastatin...

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Publicado en:PLoS One
Autores principales: Park, Kyung-Yeon, Oh, Euichaul, Kwak, Mi-Kyoung, Jun, Hyun Sik, Heo, Tae-Hwe
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780828/
https://ncbi.nlm.nih.gov/pubmed/26950217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150791
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