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Quantitative and combinatory determination of in situ phosphorylation of tau and its FTDP-17 mutants
Tau is hyperphosphorylated in the brains of patients with tauopathies, such as Alzheimer’s disease and frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). However, neither the mechanism of hyperphosphorylation nor its contribution to pathogenesis is known. We applied Phos-tag...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027580/ https://ncbi.nlm.nih.gov/pubmed/27641626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33479 |
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