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Physiological and pathological phosphorylation of tau by Cdk5
Hyperphosphorylation of microtubule-associated protein tau is one of the major pathological events in Alzheimer’s disease (AD) and other related neurodegenerative diseases, including frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). Mutations in the tau gene MAPT are a cau...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4097945/ https://ncbi.nlm.nih.gov/pubmed/25076872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2014.00065 |
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