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A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates
Despite the critical need, no previous research has substantiated safe opioid analgesics without abuse liability in primates. Recent advances in medicinal chemistry have led to the development of ligands with mixed mu opioid peptide (MOP)/nociceptin-orphanin FQ peptide (NOP) receptor agonist activit...
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027459/ https://ncbi.nlm.nih.gov/pubmed/27573832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605295113 |
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