Orvinols with Mixed Kappa/Mu Opioid Receptor Agonist Activity

[Image: see text] Dual-acting kappa opioid receptor (KOR) agonist and mu opioid receptor (MOR) partial agonist ligands have been put forward as potential treatment agents for cocaine and other psychostimulant abuse. Members of the orvinol series of ligands are known for their high binding affinity t...

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Detalhes bibliográficos
Main Authors: Greedy, Benjamin M., Bradbury, Faye, Thomas, Mark P., Grivas, Konstantinos, Cami-Kobeci, Gerta, Archambeau, Ashley, Bosse, Kelly, Clark, Mary J., Aceto, Mario, Lewis, John W., Traynor, John R., Husbands, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646402/
https://ncbi.nlm.nih.gov/pubmed/23438330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301543e
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