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Mixed Kappa/Mu Opioid Receptor Agonists: The 6β-Naltrexamines

Ligands from the naltrexamine series have consistently demonstrated agonist activity at kappa opioid receptors (KOR), with varying activity at the mu opioid receptor (MOR). Various 6β-cinnamoylamino derivatives were made with the aim of generating ligands with a KOR agonist/MOR partial agonist profi...

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Detalhes bibliográficos
Main Authors: Cami-Kobeci, Gerta, Neal, Adrian P., Bradbury, Faye A., Purington, Lauren C., Aceto, Mario D., Harris, Louis S., Lewis, John W., Traynor, John R., Husbands, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070388/
https://ncbi.nlm.nih.gov/pubmed/19253970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8015552
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