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Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist properties
Chronic use of mu-opioid agonists has been shown to cause neurochemical adaptations resulting in tolerance and dependence. While the analgesic effects of these drugs are mediated by mu-opioid receptors (MOR), several studies have shown that antagonism or knockdown of delta-opioid receptors (DOR) can...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788680/ https://ncbi.nlm.nih.gov/pubmed/19788201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9007483 |
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