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Pentapeptides displaying mu opioid receptor agonist and delta opioid receptor partial agonist/antagonist properties

Chronic use of mu-opioid agonists has been shown to cause neurochemical adaptations resulting in tolerance and dependence. While the analgesic effects of these drugs are mediated by mu-opioid receptors (MOR), several studies have shown that antagonism or knockdown of delta-opioid receptors (DOR) can...

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書誌詳細
主要な著者: Purington, Lauren C., Pogozheva, Irina D., Traynor, John R., Mosberg, Henry I.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788680/
https://ncbi.nlm.nih.gov/pubmed/19788201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9007483
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