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Modulation of Opioid Receptor Ligand Affinity and Efficacy Using Active and Inactive State Receptor Models
Mu opioid receptor (MOR) agonists are widely used for the treatment of pain; however chronic use results in the development of tolerance and dependence. It has been demonstrated that co-administration of a MOR agonist with a delta opioid receptor (DOR) antagonist maintains the analgesia associated w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465523/ https://ncbi.nlm.nih.gov/pubmed/22882801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12014 |
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