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Aminothiazolomorphinans with Mixed Kappa and Mu Opioid Activity
A series of N-substituted and N′-substituted aminothiazole-derived morphinans (5) were synthesized for expanding the structure-activity relationships of aminothiazolo-morphinans. Although their affinities were somewhat lower than their prototype aminothiazolo-N-cyclopropylmorphinan (3), 3-aminothiaz...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3068608/ https://ncbi.nlm.nih.gov/pubmed/21351746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101542c |
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