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Synthesis and Pharmacological Evaluation Aminothiazolomorphinans at Mu and Kappa Opioid Receptors

Previous studies with aminothiazolomorphinans suggested that this class of opioid ligands may be useful as a potential pharmacotherapeutic to decrease drug abuse. Novel aminothiazole derivatives of cyclorphan were prepared in order to evaluate a series of aminothiazolomorphinans with varying pharmac...

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Detalhes bibliográficos
Main Authors: Provencher, Brian A., Sromek, Anna W., Li, Wei, Russell, Shayla, Chartoff, Elena, Knapp, Brian I., Bidlack, Jean M., Neumeyer, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880591/
https://ncbi.nlm.nih.gov/pubmed/24107104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401290y
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