Nalaganje...
PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
Mammalian prions are unusual infectious agents, as they are thought to consist solely of aggregates of misfolded prion protein (PrP). Generation of synthetic prions, composed of recombinant PrP (recPrP) refolded into fibrils, has been utilised to address whether PrP aggregates are, indeed, infectiou...
Shranjeno v:
| izdano v: | Acta Neuropathol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5023723/ https://ncbi.nlm.nih.gov/pubmed/27376534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-016-1594-5 |
| Oznake: |
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